Chronic Venous Insufficiency (CVI) – Overview

Chronic Venous Insufficiency (CVI) is a long-term condition characterized by inadequate blood flow in the veins of the lower limbs. This occurs when vein valves or walls become weakened or damaged, causing blood to pool in the legs.

Health Apr 21, 2025 18 Add to Reading List

As a result, symptoms such as swelling, varicose veins, skin discoloration, and leg ulcers can develop. Common risk factors include prolonged periods of sitting or standing, obesity, aging, pregnancy, and a genetic predisposition to venous disorders. Symptoms can vary in severity but often include feelings of heaviness, cramping, pain, and swelling in the legs. Early detection and prompt treatment are essential for managing the progression of the condition and improving the patient's quality of life.

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CVI Epidemiological Segmentation (2020–2034) – 7MM

Overall Prevalence of CVI
Prevalence by Gender
Prevalence by Age Group
Number of Treatable Cases

CVI Epidemiology (2023 Snapshot)
As of 2023, Chronic Venous Disease (CVD), including CVI, impacted approximately 463 million people in the seven major markets (7MM).

The United States reported about 6.2 million prevalent cases of CVI.
In the US, the C1 stage was the most frequently diagnosed form of the disease.
Epidemiological trends indicate a higher prevalence among females and older adults, highlighting the progressive nature of the condition.

CVI Market Overview
The market for CVI therapies and devices in the 7MM was valued at an estimated USD 2 billion in 2023.

Market Growth Drivers

Increased awareness about CVI and its related health issues is driving the uptake of advanced diagnostic and treatment options.
Continuous technological advancements, particularly in minimally invasive treatments like endovenous procedures and next-gen devices, are transforming the delivery of care.

Market Challenges

The high cost of advanced treatments and devices may restrict access, particularly in healthcare systems with limited financial resources.
Encouraging patient adherence to lifestyle changes and the use of compression therapy remains a significant challenge in effectively managing CVI.

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Emerging CVI Treatment Devices